| 產(chǎn)品編號 | bsm-61331R |
| 英文名稱 | CDC25C Recombinant Rabbit mAb |
| 中文名稱 | 細(xì)胞分裂周期蛋白25C重組兔單抗 |
| 別 名 | CDC25; CDC25C; Cell division cycle 25 homolog C; MPIP3; PPP1R60. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 10H10 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53 kDa |
| 檢測分子量 | 60 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human CDC25C: 11-63 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.When phosphorylated, highly effective in activating G2 cells into prophase.Directly dephosphorylates CDK1 and activates its kinase activity. SWISS: P30307 Gene ID: 995 CDC25家族的組成哺乳動物中CDC25家族一共包括3種同源異構(gòu)體（CDC25A、CDC25B、CDC25C），約有50%的序列同源，是一組在細(xì)胞周期調(diào)控中發(fā)揮巨大作用的蘇/酪氨酸雙功能酶 。不同的CDC25家族蛋白在細(xì)胞周期中的作用時相亦有差異，CDC25A和CDC25C分別在S期和M期發(fā)揮主要作用。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with Cdc25C monoclonal antibody, unconjugated (bsm-61331R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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