| 產(chǎn)品編號(hào) | bsm-61318R |
| 英文名稱 | CaMK2 alpha Recombinant Rabbit mAb |
| 中文名稱 | 鈣/鈣調(diào)素依賴蛋白激酶2α重組兔單抗 |
| 別 名 | alpha CaMKII; Camk2a; CAMKA; CaMKII; CaMKIINalpha; PK2CDD; PKCCD. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 5D17 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,Flow-Cyt=1:20-50,IP=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54 kDa |
| 檢測(cè)分子量 | 54 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human CaMKII alpha: 34-84 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in various processes, such as synaptic plasticity, neurotransmitter release and long-term potentiation.Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission. SWISS: Q9UQM7 Gene ID: 818 CaMK2b也是絲/蘇氨基酸激酶的一種，同屬于Ca++/鈣調(diào)素依賴性蛋白質(zhì)激酶家族成員。鈣／鈣調(diào)素依賴性蛋白激酶Ⅱb（CaMKⅡb）廣泛分布于中樞神經(jīng)系統(tǒng)內(nèi)，參與調(diào)節(jié)神經(jīng)遞質(zhì)的合成釋放、信號(hào)轉(zhuǎn)導(dǎo)和突觸可塑性的形成以及磷酸化蛋白 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with CaMK2 alpha monoclonal antibody, unconjugated (bsm-61318R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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